Travel the world with the Thornberrys and come face-to-face with blue sheep in Nepal, emus in Australia, marmots in Pakistan, flash floods in Siberia, Egyptian burial chambers, a runaway hot air balloon, a rock slide on the Karakoram Highway and more!
| Actor | Role |
|---|---|
 Lacey ChabertEliza Thornberry (voice) | Eliza Thornberry (voice) |
 Jodi CarlisleMarianne Thornberry (voice) | Marianne Thornberry (voice) |
 Tim CurryNigel Thornberry (voice) | Nigel Thornberry (voice) |
 FleaDonnie Thornberry (voice) | Donnie Thornberry (voice) |
 Danielle HarrisDebbie Thornberry (voice) | Debbie Thornberry (voice) |
 Tom KaneDarwin (voice) | Darwin (voice) |