 Lacey ChabertEliza Thornberry (voice) | Eliza Thornberry (voice) |
 Jodi CarlisleMarianne Thornberry (voice) | Marianne Thornberry (voice) |
 Tim CurryNigel Thornberry (voice) | Nigel Thornberry (voice) |
 FleaDonald 'Donnie' Michael Thornberry (voice) | Donald 'Donnie' Michael Thornberry (voice) |
 Danielle HarrisDebbie Thornberry (voice) | Debbie Thornberry (voice) |
 Tom KaneDarwin (voice) | Darwin (voice) |
 Betty WhiteGrandma Sophie (voice) | Grandma Sophie (voice) |
| AAlan Henry BrownSri Mayasandra (voice) | Sri Mayasandra (voice) |
 Arthur BurghardtRhino / Monkey (voice) | Rhino / Monkey (voice) |
 Cara DeLiziaBaru / Monkey (voice) | Baru / Monkey (voice) |
 Moira QuirkRehabilitation Worker / Monkey (voice) | Rehabilitation Worker / Monkey (voice) |
 Dwight SchultzBadouk / Monkey / Poacher (voice) | Badouk / Monkey / Poacher (voice) |
| TTuan TranKickboxing Instructor (voice) | Kickboxing Instructor (voice) |
 Alfre WoodardMedicine Woman (voice) | Medicine Woman (voice) |
 Dee Bradley BakerParrots (voice) | Parrots (voice) |
 Patti DeutschFemale Rhinoceros Hornbill (voice) | Female Rhinoceros Hornbill (voice) |
 Clyde KusatsuSun Bear (voice) | Sun Bear (voice) |
 David PaymerMale Rhinoceros Hornbill (voice) | Male Rhinoceros Hornbill (voice) |
| MMaureen QuinnLugan (voice) | Lugan (voice) |
 Pamela AdlonSaiful (voice) | Saiful (voice) |
| JJusak BernhardTribal Man / Villager / Poacher (voice) | Tribal Man / Villager / Poacher (voice) |
| DDenny ChandraVillager (voice) | Villager (voice) |
 Tania GunadiVillager / Forest Animal (voice) | Villager / Forest Animal (voice) |
| MMalik NasutionVillager (voice) | Villager (voice) |
 Benny TjandraVillager (voice) | Villager (voice) |
 Earl BoenBearded Pig / Poacher (voice) | Bearded Pig / Poacher (voice) |
 Leila KenzleSquirrel / Forest Animal (voice) | Squirrel / Forest Animal (voice) |
 Candi MiloCivat Cat / Mousedeer / Forest Animal (voice) | Civat Cat / Mousedeer / Forest Animal (voice) |
 Pat MusickOna / Owl / Forest Animal (voice) | Ona / Owl / Forest Animal (voice) |
 Julia NicksonVillager / Forest Animal / Donnie's Mother (voice) | Villager / Forest Animal / Donnie's Mother (voice) |