 Kenneth BranaghHercule Poirot | Hercule Poirot |
 Tom BatemanBouc | Bouc |
 Michelle PfeifferCaroline Hubbard | Caroline Hubbard |
 Johnny DeppEdward Ratchett | Edward Ratchett |
 Josh GadHector MacQueen | Hector MacQueen |
 Willem DafoeGerhard Hardman | Gerhard Hardman |
 Judi DenchPrincess Dragomiroff | Princess Dragomiroff |
 Derek JacobiEdward Henry Masterman | Edward Henry Masterman |
 Leslie Odom Jr.Dr. Arbuthnot | Dr. Arbuthnot |
 Daisy RidleyMiss Mary Debenham | Miss Mary Debenham |
 Penélope CruzPilar Estravados | Pilar Estravados |
 Olivia ColmanHildegarde Schmidt | Hildegarde Schmidt |
 Lucy BoyntonCountess Elena Andrenyi | Countess Elena Andrenyi |
 Marwan KenzariPierre Michel | Pierre Michel |
 Manuel Garcia-RulfoBiniamino Marquez | Biniamino Marquez |
 Sergei PoluninCount Rudolph Andrenyi | Count Rudolph Andrenyi |
 Paapa EssieduYoung Policeman | Young Policeman |
| YYassine ZeroualYoung Boy | Young Boy |
 Asan N'JieHotel Waiter | Hotel Waiter |
 Michael RouseBritish Police Chief Inspector | British Police Chief Inspector |
 Elliot LeveyRabbi | Rabbi |
 David AnnenPriest | Priest |
 Joseph LongImam | Imam |
 Andy ApolloArmed Policeman | Armed Policeman |
 Hadley FraserBritish Military Escort | British Military Escort |
 Ziad AbazaArab Shipmate | Arab Shipmate |
 Nari Blair-MangatWaiter | Waiter |
 Luke BradyWaiter | Waiter |
 Miltos YerolemouOld Turk Baker | Old Turk Baker |
 Kathryn WilderProstitute | Prostitute |
