Molly Mahoney is the awkward and insecure manager of Mr. Magorium's Wonder Emporium—the strangest, most fantastic and most wonderful toy store in the world. After Mr. Magorium bequeaths the store to her, a dark and ominous change begins to take over the once-remarkable Emporium.
| Actor | Role |
|---|---|
 Dustin HoffmanMr. Edward Magorium | Mr. Edward Magorium |
 Natalie PortmanMolly Mahoney | Molly Mahoney |
 Jason BatemanHenry Weston | Henry Weston |
 Zach MillsEric Applebaum | Eric Applebaum |
 Jonathan PottsDr. Sage | Dr. Sage |
 Rebecca NorthanEllie Applebaum | Ellie Applebaum |
| DDavid RendallTim | Tim |
| JJade CohenKangaroo Girl | Kangaroo Girl |
 Marcia BennettLora | Lora |
 Ted LudzikBellini | Bellini |
| MMadalena BrancatellaJessica | Jessica |
 Paula BoudreauBrenda | Brenda |
 Mike RealbaDave Wolf | Dave Wolf |
 Steve WhitmireKermit the Frog (voice) | Kermit the Frog (voice) |
| LLiam Powley-WebsterAndy | Andy |
| OOliver MasudaJordan | Jordan |
| SSamantha HarveyCassie | Cassie |
 Jesse BostickDerek | Derek |
 Isaac DurnfordJason | Jason |
 Daniyah YsraylJimmy | Jimmy |
 Dash GrundyAri | Ari |
 Dylan AuthorsMark | Mark |
| AAidan KoperBrett | Brett |
| LLin Lin FengAngie | Angie |
| HHe WenLarry | Larry |
| GGan ZhenDavid | David |
| QQuancetia HamiltonGia | Gia |
 Kiele SanchezMrs. Goodman | Mrs. Goodman |
 David CollinsTom | Tom |
 Matt BaramEddie, the Dentist | Eddie, the Dentist |