The life and times of famed Paraguayan musician Agustín Pío Barrios, from the years of his youth to his international success.
| Actor | Role |
|---|---|
 Damián AlcázarAgustín Pío Barrios | Agustín Pío Barrios |
| AAparecida PetrowkyGloria Silva | Gloria Silva |
| JJoaquín SerranoFrancisco Martín Barrios | Francisco Martín Barrios |
 Celso FrancoAgustín Pío Barrios (joven) | Agustín Pío Barrios (joven) |
 Lali GonzálezIsabel Villalba | Isabel Villalba |
 Fabián GianolaFlorencio Parravicini | Florencio Parravicini |
| IIñaki MorenoAndrés Segovia | Andrés Segovia |
 Silvio RodasNicolino Pellegrini | Nicolino Pellegrini |
| CCarmen BrianoMadre Isabel Villalba | Madre Isabel Villalba |
| JJorge RattiAmigo de juventud 3 | Amigo de juventud 3 |
| FFiorella MiglioreAmiga de Isabel 1 | Amiga de Isabel 1 |