 Jim CarreyAndy Kaufman / Tony Clifton | Andy Kaufman / Tony Clifton |
 Danny DeVitoGeorge Shapiro | George Shapiro |
 Courtney LoveLynne Margulies | Lynne Margulies |
 Paul GiamattiBob Zmuda | Bob Zmuda |
 Vincent SchiavelliMaynard Smith | Maynard Smith |
 Peter BonerzEd Weinberger | Ed Weinberger |
 Jerry LawlerHimself | Himself |
 Gerry BeckerStanley Kaufman | Stanley Kaufman |
 Leslie LylesJanice Kaufman | Janice Kaufman |
| GGreyson Erik PendryLittle Michael Kaufman | Little Michael Kaufman |
| BBrittany ColonnaBaby Carol Kaufman | Baby Carol Kaufman |
| BBobby BorielloLittle Andy Kaufman | Little Andy Kaufman |
 George ShapiroMr. Besserman | Mr. Besserman |
 Budd FriedmanHimself | Himself |
| TTom DreesenWiseass Comic | Wiseass Comic |
| TThomas ArmbrusterImprov Piano Player | Improv Piano Player |
 Pamela AbdyDiane Barnett | Diane Barnett |
 Wendy PollandLittle Wendy | Little Wendy |
| CCash OshmanYogi | Yogi |
 Matt PriceMeditation Student | Meditation Student |
 Christina CabotMeditation Student | Meditation Student |
 Richard BelzerRichard Belzer | Richard Belzer |
| MMelanie VeseyCarol Kaufman | Carol Kaufman |
 Michael KellyMichael Kaufman | Michael Kaufman |
 Miles ChapinSNL Assistant | SNL Assistant |
| IIsadore RosenfeldNBC Executive | NBC Executive |
 Molly SchafferMaynard Smith's Assistant | Maynard Smith's Assistant |
| HHoward WestABC Executive | ABC Executive |
 Greg TravisABC Executive | ABC Executive |
 Maureen MuellerABC Executive | ABC Executive |
