A male-centric take on contemporary relationships, where three guy friends look for love and commitment.
| Actor | Role |
|---|---|
 Scott CohenDave Segel | Dave Segel |
 John StamosCal Scoppa | Cal Scoppa |
 Annabeth GishGreta Siegel | Greta Siegel |
 Paulina PorizkovaLily Kildear | Lily Kildear |
 Michael Leydon CampbellJake Elovitch | Jake Elovitch |
 Tara ReidEmily | Emily |
 Linda LarkinAnnette | Annette |
 KaDee StricklandMolly | Molly |
| SSarah LitzsingerAndrea | Andrea |
 Eric ZuckermanSummons Server | Summons Server |
| JJohn HeinleinLeering mover | Leering mover |
 Elliot VillarOblivious mover | Oblivious mover |
| MMike TarantoMike the bartender | Mike the bartender |
| KKatie OrensteinHot chick at basketball court | Hot chick at basketball court |
| KKathleen TruittDeparting party girl | Departing party girl |
| SSteve Mastro Jr.Party ass-grabber | Party ass-grabber |
 Melanie LewisCrazy dancing chick | Crazy dancing chick |
| NNeil TuritzHunk at water cooler | Hunk at water cooler |
 Stephanie KurtzubaSheila | Sheila |
 John RothmanDave's Lawyer | Dave's Lawyer |
| KKaren MaleckiOffice Eye Candy (as Karen Waiton) | Office Eye Candy (as Karen Waiton) |
 Brette TaylorEmily (uncredited) | Emily (uncredited) |