In the year 2898 AD, around 6000 years after Kurukshetra war, Ashwatthama gears up for his final battle of redemption at the sign of hope in a dystopian world and Bhairava, a wisecracking and self-interested bounty hunter, tired of the perilous life becomes the hurdle in the process.
| Actor | Role |
|---|---|
 Amitabh BachchanAshwatthama | Ashwatthama |
 PrabhasBhairava | Bhairava |
 Deepika PadukoneSUM-80 "Sumathi" | SUM-80 "Sumathi" |
 Kamal HaasanSupreme Yaskin | Supreme Yaskin |
 Saswata ChatterjeeManas | Manas |
 ShobanaMariam | Mariam |
 Rajendra PrasadRumi | Rumi |
 PasupathyVeeran | Veeran |
 Anna BenKyra | Kyra |
| KKeya NairRaia | Raia |
| HHarshith MalgireddyLuke | Luke |
| AAyaz PashaAjju | Ajju |
| HHumhuKrane | Krane |
| KKavya RamachandranLilly | Lilly |
 Anil GeorgeBani | Bani |
 Disha PataniRoxie | Roxie |
 BrahmanandamRajan | Rajan |
 Keerthy SureshBU-JZ-1 'Bujji' (voice) | BU-JZ-1 'Bujji' (voice) |
| VVinay KumarSirius | Sirius |
 Sanjay RathaShatru | Shatru |
| DDhruv SincroRaider No. 1 | Raider No. 1 |
| VVenkata RamanaRonnie | Ronnie |
| HHamish BoydYuri | Yuri |
| AAdvait ChauhanIssac | Issac |
| SSanghwa ShinLeon | Leon |
| PPrashant YarramilliSaanu's Father | Saanu's Father |
| BBaby SanvithaSaanu | Saanu |
| RRasoolNaiko | Naiko |
| CChandra MohanGoku | Goku |
| SSai KrishnaKrane's Slave | Krane's Slave |