The mysterious island of Houraijima has reappeared after 50 years, and with its reappearance has brought the attack of four gods, the Shitoushin, who have their eyes set on the powers that protect and sustain the island. Now it's up to Inuyasha and his friends, along with Sesshoumaru, to find a way to defeat the powerful Shitoushin.
| Actor | Role |
|---|---|
 Kappei YamaguchiInuyasha (voice) | Inuyasha (voice) |
 Satsuki YukinoKagome Higurashi (voice) | Kagome Higurashi (voice) |
 Koji TsujitaniMiroku (voice) | Miroku (voice) |
 Houko KuwashimaSango (voice) | Sango (voice) |
 Kumiko WatanabeShippo (voice) | Shippo (voice) |
 Noriko HidakaKikyo (voice) | Kikyo (voice) |
 Ken NaritaSesshomaru (voice) | Sesshomaru (voice) |
 ChoJaken (voice) | Jaken (voice) |
 Mamiko NotoRin (voice) | Rin (voice) |
 Nobutoshi CannaRyūra (voice) | Ryūra (voice) |
 Nobuo TobitaKyōra (voice) | Kyōra (voice) |
 Takeshi KusaoJūra (voice) | Jūra (voice) |
| TTadahisa SaizenGōra (voice) | Gōra (voice) |
 Fumiko OrikasaAsagi (voice) | Asagi (voice) |
 Yu KobayashiDai (voice) | Dai (voice) |
 Reiko KiuchiRoku (voice) | Roku (voice) |
 Kaori ShimizuShion (voice) | Shion (voice) |
 Yuki MasudaMoegi (voice) | Moegi (voice) |
 Emi MotoiAi (voice) | Ai (voice) |
 Tomiko VanLady Kanade (voice) | Lady Kanade (voice) |
 Mitsuki SaigaKujaku (voice) | Kujaku (voice) |