Andy Goodrich's life is upended when his wife enters a rehab program, leaving him on his own with their young kids. Goodrich leans on his daughter from his first marriage, Grace, as he ultimately evolves into the father Grace never had.
| Actor | Role |
|---|---|
 Michael KeatonAndy | Andy |
 Mila KunisGrace | Grace |
 Carmen EjogoLola | Lola |
 Michael UrieTerry | Terry |
 Kevin PollakCy | Cy |
 Vivien Lyra BlairBillie | Billie |
 Nico HiragaJonny | Jonny |
 Jacob KoperaMose | Mose |
 Danny DeferrariPete | Pete |
 Poorna JagannathanDr. Verma | Dr. Verma |
 Andrew LeedsGreg | Greg |
 Laura BenantiNaomi | Naomi |
 Andie MacDowellAnn | Ann |
 Kimberly CondictCecile | Cecile |
 Noa FisherTali | Tali |
 Jessica HellerBecca | Becca |
 Monique MosesTeacher | Teacher |
 Carlos SolórzanoAlexander | Alexander |
 Chloe TroastChloe | Chloe |
 Liza TreygerComedian | Comedian |
 Lois ShihNeighbor | Neighbor |
 Carlos RagasBald Man | Bald Man |
 Sydney MilesIris | Iris |
 Miles AndersonBarry Klein | Barry Klein |
 Michael ChieffoEd | Ed |
 Roshni ShuklaSandy | Sandy |
 Crosby FitzgeraldAnnie | Annie |
| CChander DayaArtist (uncredited) | Artist (uncredited) |
| MMichelle Marie JacquotArtist (uncredited) | Artist (uncredited) |
 Dominique StarDrummer (uncredited) | Drummer (uncredited) |