The lives of a group of young doctors, nurses, and administrators working at an underfunded Los Angeles county hospital.
| Actor | Role |
|---|---|
 Agam DarshiTalaikha | Talaikha |
 Tonye PatanoLiz | Liz |
 Michael B. JordanTravis | Travis |
 Michael ImperioliDr. David Mercer | Dr. David Mercer |
 Jason RitterJack Malloy | Jack Malloy |
 Aimee GarciaRosa | Rosa |
 Patrick FischlerHendricks | Hendricks |
 Emily RiosLucy | Lucy |
 Jess WeixlerErica Kinsey | Erica Kinsey |
 Sumalee MontanoMalea | Malea |
 Norbert Leo ButzBilly | Billy |
 Brianne TjuOlivia | Olivia |
 Roberto SanchezMarcelino Santos | Marcelino Santos |
 Fernanda RomeroNurse Rosario | Nurse Rosario |
 Jessica Marie GarciaVicky Santos | Vicky Santos |
 Phil AbramsAbe Goldenrod | Abe Goldenrod |
 Yaani King MondscheinAngela | Angela |
 Evan ArnoldER Doc Margolis | ER Doc Margolis |
 Stacie GreenwellMrs. Warner | Mrs. Warner |
 Burt BulosER Doc Aquino | ER Doc Aquino |
 Toby HolguinDad #2 | Dad #2 |
 Stephanie Maura SanchezEmilia Rodriguez | Emilia Rodriguez |
 Frank GallegosOfficer Wade | Officer Wade |