Barbie and Ken are having the time of their lives in the colorful and seemingly perfect world of Barbie Land. However, when they get a chance to go to the real world, they soon discover the joys and perils of living among humans.
| Actor | Role |
|---|---|
 Margot RobbieBarbie | Barbie |
 Ryan GoslingKen | Ken |
 America FerreraGloria | Gloria |
 Ariana GreenblattSasha | Sasha |
 Issa RaeBarbie | Barbie |
 Kate McKinnonBarbie | Barbie |
 Alexandra ShippBarbie | Barbie |
 Emma MackeyBarbie | Barbie |
 Hari NefBarbie | Barbie |
 Sharon RooneyBarbie | Barbie |
 Ana Cruz KayneBarbie | Barbie |
 Ritu AryaBarbie | Barbie |
 Dua LipaBarbie | Barbie |
 Nicola CoughlanBarbie | Barbie |
 Emerald FennellMidge | Midge |
 Simu LiuKen | Ken |
 Kingsley Ben-AdirKen | Ken |
 Ncuti GatwaKen | Ken |
 Scott EvansKen | Ken |
 John CenaKen | Ken |
 Michael CeraAllan | Allan |
 Rhea PerlmanRuth | Ruth |
 Helen MirrenNarrator (voice) | Narrator (voice) |
 Will FerrellMattel CEO | Mattel CEO |
 Connor SwindellsAaron Dinkins | Aaron Dinkins |
 Jamie DemetriouMattel Executive #1 | Mattel Executive #1 |
 Andrew LeungMattel Executive #2 | Mattel Executive #2 |
 Will MerrickYoung Mattel Employee | Young Mattel Employee |
 Zheng Xi YongAn Even Younger Mattel Employee | An Even Younger Mattel Employee |
 Asim ChaudhryWarehouse Employee | Warehouse Employee |