Ana and Alberto get married. Their best friends warn them about the seven year itch: the usual time when a couple starts experiencing big problems in their relationship. We will follow Ana and Alberto on their marriage until they reach their seven year itch.
| Actor | Role |
|---|---|
| RRoberto PalazuelosPepe | Pepe |
 Ximena HerreraAna | Ana |
| Ximena HerreraAlberto | Alberto |
 Cristián de la FuenteBernardo | Bernardo |
 Fernando BecerrilNot listed | Not listed |
| AAlex SirventFranco | Franco |
 María SortéNot listed | Not listed |
| AAlejandra ProcunaTessie | Tessie |
| MMontserrat OlivierNot listed | Not listed |
 Katherine PortoLaura | Laura |
 Jorge CamposHimself | Himself |
 Jacqueline AndereNot listed | Not listed |
 Víctor GonzálezAlberto | Alberto |
| AArturo García TenorioSergio | Sergio |
| DDaniela SavalaAbogada | Abogada |
 Yolanda AndradeLuna | Luna |
| DDaniel VillarEmmanuel | Emmanuel |
| BBárbara CoppelNot listed | Not listed |
| BBarbara GrahamNot listed | Not listed |
| RRicardo KorkowskiNot listed | Not listed |
| MMauricio LuleNot listed | Not listed |
| PPablo FulgueiraNot listed | Not listed |
| JJoss WaleskaNot listed | Not listed |
| JJosé Antonio SánchezNot listed | Not listed |