Penn Zero is not your average kid - every day, he's zapped into another dimension with his friends to save the world.
| Actor | Role |
|---|---|
 Thomas MiddleditchPenn Zero (voice) | Penn Zero (voice) |
 Tania GunadiSashi Kobayashi (voice) | Sashi Kobayashi (voice) |
 Adam DevineBoone Wiseman (voice) | Boone Wiseman (voice) |
 Alfred MolinaRippen (voice) | Rippen (voice) |
 Larry WilmoreLarry (voice) | Larry (voice) |
 Sam LevinePhyllis (voice) | Phyllis (voice) |
 Gary ColeBrock (voice) | Brock (voice) |
 Lea ThompsonVonnie (voice) | Vonnie (voice) |
 Lenny VenitoUncle Chuck (voice) | Uncle Chuck (voice) |
 Rosie PerezAunt Rose (voice) | Aunt Rose (voice) |