On a special inner city street, the inhabitants—human and muppet—teach preschoolers basic educational and social concepts using comedy, cartoons, games, and songs.
| Actor | Role |
|---|---|
 Frank OzBert | Bert |
 Sonia ManzanoMaria Figueroa Rodriguez | Maria Figueroa Rodriguez |
 Roscoe OrmanGordon Robinson | Gordon Robinson |
 Martin P. RobinsonTelly Monster / Aloysius Snuffleupagus / Irvine / Slimey (voice) | Telly Monster / Aloysius Snuffleupagus / Irvine / Slimey (voice) |
 Suki LopezNina | Nina |
 Violet TinnirelloCharlie | Charlie |
 Jennifer BarnhartZoe (voice) | Zoe (voice) |
 Ryan DillonElmo (voice) | Elmo (voice) |
 Alan MuraokaAlan | Alan |