 James Badge DaleRobert Leckie | Robert Leckie |
 Jon SedaJohn Basilone | John Basilone |
 Joseph MazzelloEugene Sledge | Eugene Sledge |
 Ashton HolmesPFC Sidney Phillips | PFC Sidney Phillips |
 Jacob PittsPFC Bill 'Hoosier' Smith | PFC Bill 'Hoosier' Smith |
 Rami MalekPFC Merriell 'Snafu' Shelton | PFC Merriell 'Snafu' Shelton |
 William SadlerLt Col. Lewis 'Chesty' Puller | Lt Col. Lewis 'Chesty' Puller |
 Jon BernthalSgt. Manuel 'Manny' Rodriguez | Sgt. Manuel 'Manny' Rodriguez |
 Matt CravenDr. Grant | Dr. Grant |
 Noel FisherPvt. Hamm | Pvt. Hamm |
 Caroline DhavernasVera Keller | Vera Keller |
 Brendan FletcherBill Leyden | Bill Leyden |
 Isabel LucasGwen | Gwen |
 Annie ParisseLena Mae Riggi-Basilone | Lena Mae Riggi-Basilone |
 Claire van der BoomStella | Stella |
 Keith NobbsPFC Wilbur 'Runner' Conley | PFC Wilbur 'Runner' Conley |
 Tom HanksNarrator (voice) | Narrator (voice) |
 Nicholas CooperArmy Officer | Army Officer |
 Leon Ford1st Lt. Edward 'Hillbilly' Jones | 1st Lt. Edward 'Hillbilly' Jones |
 Scott GibsonCapt. Andrew 'Ack Ack' Haldane | Capt. Andrew 'Ack Ack' Haldane |
 Martin McCannCpl. R.V. Burgin, Sgt. R.V. Burgin | Cpl. R.V. Burgin, Sgt. R.V. Burgin |
 Nathin Art ButlerPrivate Young | Private Young |
 Toby Leonard Moore2nd Lt. Stone, Sgt. Stone | 2nd Lt. Stone, Sgt. Stone |
 Josh HelmanPFC Lew ‘Chuckler’ Juergens | PFC Lew ‘Chuckler’ Juergens |
