Having faced each other on countless occasions, Yugi and Kaiba again put their pride and experience to the test in a duel that transcends dimensions.
| Actor | Role |
|---|---|
 Kenjiro TsudaSeto Kaiba (voice) | Seto Kaiba (voice) |
 Shunsuke KazamaYugi Moto (voice) | Yugi Moto (voice) |
 Hiroki TakahashiJoey Wheeler (voice) | Joey Wheeler (voice) |
| MMaki SaitoTea Gardner (voice) | Tea Gardner (voice) |
 Takayuki KondoTristan Taylor (voice) | Tristan Taylor (voice) |
 Rica MatsumotoRyo Bakura (voice) | Ryo Bakura (voice) |
 Junko TakeuchiMokuba Kaiba (voice) | Mokuba Kaiba (voice) |
 Ryou NaitouDuke Devlin (voice) | Duke Devlin (voice) |
 Kento HayashiAigami (voice) | Aigami (voice) |
 Tadashi MiyazawaSolomon Moto (voice) | Solomon Moto (voice) |
 Kazuhiro YamajiMr. Bakura (voice) | Mr. Bakura (voice) |
 Kana HanazawaSera (voice) | Sera (voice) |
 Satoshi HinoMani (voice) | Mani (voice) |
 Kendo KobayashiKudaragi (voice) | Kudaragi (voice) |
 Nozomu SasakiShadi Shin (voice) | Shadi Shin (voice) |