The lives and relationships of a colorful array of characters become irretrievably entwined: neurotic B-list TV director Orlando; his new-age wife Sonia; tempestuous couple Mauricio and Renée; and sweet, charming nurse-turned-serial killer Mamá Rosa - whose unlikely story is being covered by a reality TV series.
| Actor | Role |
|---|---|
 Juan Manuel BernalOrlando | Orlando |
 Cecilia SuárezRenée | Renée |
 José María YázpikMauricio | Mauricio |
 Mariana GajáSonia | Sonia |
 Tara ParraMamá Rosa | Mamá Rosa |
| DDonal CortésAriel | Ariel |
 Blake GibbonsMike | Mike |
 Byron ThamesJohn | John |
| EEugenio BartilottiBarbitas | Barbitas |
 Mónica HuarteNot listed | Not listed |
| CCecilia TijerinaNot listed | Not listed |
 Joaquín CosíoNot listed | Not listed |
 Tito VasconcelosNot listed | Not listed |
 Veronica SeguraNot listed | Not listed |
 Úrsula PrunedaNot listed | Not listed |
 Alejandro de la MadridNot listed | Not listed |
 Alicia EncinasNot listed | Not listed |
 Silverio PalaciosNot listed | Not listed |
| AAlejandra BogueNot listed | Not listed |