In Part Three, entitled "The Last Fight," gangster Santer Jr. attempts to seize an oil well on Indian territory. To prevent this, Winnetou and Old Shatterhand must reconcile the warring Indian tribes so that they can take up the fight against the henchmen of the criminal.
| Actor | Role |
|---|---|
 Wotan Wilke MöhringOld Shatterhand | Old Shatterhand |
 Nik XhelilajWinnetou | Winnetou |
 Iazua LariosNscho-tschi | Nscho-tschi |
 Michael MaertensFrederick Louis Santer Jr. | Frederick Louis Santer Jr. |
 Mario AdorfFrederick Louis Santer Sr. | Frederick Louis Santer Sr. |
 Milan PeschelSam Hawkens | Sam Hawkens |
 Henny ReentsBelle | Belle |
 Gustav Peter WöhlerJudge | Judge |
 Sebastian CavazzaTokvi-Kava | Tokvi-Kava |
| DDanira GovićFrau Tadeusz | Frau Tadeusz |
 Iván GallardoHäuptling der Navajo | Häuptling der Navajo |