Retired lawman Kentucky Wade and his three buddies, Mike Morales, "Dude" Hanford and "Trigger" Benton come to Brimstone and help their friends Larry Munro and his sister, Lucy , in their fight to retain control of Larry's rich ore mine. "Doc" Hardy , as an old friend of Wade's, joins them in their efforts to keep Matt Keeler , the scheming owner of "The Brimstone News", from his efforts to wrest control of Munro's property and mine. Keller employs a legion of henchmen, and sidelines at running runs guns to Red Hatchet and his tribe so they can also get in on the fray against the Munro's and Kentucky and friends.
| Actor | Role |
|---|---|
 Johnny Mack BrownKentucky Wade | Kentucky Wade |
| GGeorge ShelleyDude Hanford | Dude Hanford |
 Lynn GilbertLucy Munro | Lucy Munro |
 Frank YaconelliMike Morales | Mike Morales |
 Bob KortmanTrigger Benton | Trigger Benton |
 Russell SimpsonMatt Keeler | Matt Keeler |
 Walter MillerDoc Hardy | Doc Hardy |
 Charles StevensBuckskin Frank, Henchman | Buckskin Frank, Henchman |
| FFrank McGlynn Jr.Larry Munro | Larry Munro |
 Francis McDonaldAssayer Purvis, member of the Secret 7 | Assayer Purvis, member of the Secret 7 |
 Al BridgeSteve Claggett, Henchman | Steve Claggett, Henchman |
 Chief ThunderbirdChief Red Hatchet | Chief Red Hatchet |
| RRobert McClungMouth Organ Kid | Mouth Organ Kid |
 Edward LeSaintSheriff | Sheriff |
 Joseph W. GirardJudge Lawrence | Judge Lawrence |
 Jack Rube CliffordCorey, member of the Secret 7 | Corey, member of the Secret 7 |
 William RoyleBraden, member of the Secret 7 | Braden, member of the Secret 7 |
| BBruce MitchellRancher Tobe Driscoll, member of the Secret 7 | Rancher Tobe Driscoll, member of the Secret 7 |
 Miki MoritaChan, second Cook | Chan, second Cook |