Is Alixe and Gwen's sexual disagreement the cause of their problems, or are their problems the cause of their sexual disagreement? And how should an artist nurture her vision: by seeking adventures on the edge or by staying home and writing poems? What's more real, our fantasies, or what we actually do? In Who's the Top? there are no right answers, just musical numbers.
| Actor | Role |
|---|---|
 Marin HinkleAlixe | Alixe |
 Brigitte BakoGwen | Gwen |
 Steve BuscemiCymon | Cymon |
 RenoWoman at Toy Store | Woman at Toy Store |
| MMaureen AngelosBuzz | Buzz |
 Shelly MarsMars | Mars |
| BBrian BurchillMan in Toy Store | Man in Toy Store |
| CCindra FeuerSales Clerk | Sales Clerk |
 Brooke TansleyVanilla | Vanilla |
| FFrancis MaiorinoBartender (uncredited) | Bartender (uncredited) |