Simon Cowell is shot at his birthday party, and Ant and Dec are accused and forced to run.
| Actor | Role |
|---|---|
 Anthony McPartlinSelf | Self |
 Declan DonnellySelf | Self |
 Simon CowellSimon Cowell | Simon Cowell |
 Mark AustinNewsreader | Newsreader |
 Ashley BanjoParty Guest | Party Guest |
 Christopher BigginsParty Guest | Party Guest |
 Emma BuntonParty Guest | Party Guest |
 Ashleigh ButlerParty Guest | Party Guest |
 Craig DavidParty Guest | Party Guest |
 Warwick DavisParty Guest | Party Guest |
 Alesha DixonParty Guest | Party Guest |
 Caroline FlackParty Host | Party Host |
 Emilia FoxDr. Nikki Alexander | Dr. Nikki Alexander |
 Leigh FrancisKeith Lemon | Keith Lemon |
 Amanda HoldenParty Guest | Party Guest |
 Perri KielyParty Guest | Party Guest |
 Ewen MacIntoshCafé Owner | Café Owner |
 Piers MorganParty Guest | Party Guest |
 Stephen MulhernParty Guest | Party Guest |
 Olly MursParty Host | Party Host |
 Sharon OsbourneSharon Osbourne | Sharon Osbourne |
 Vicky PattisonParty Guest | Party Guest |
 PudseySelf | Self |
 Ashley RobertsParty Guest | Party Guest |
 SinittaParty Guest | Party Guest |
 Stacey SolomonParty Guest | Party Guest |
 David WalliamsParty Guest | Party Guest |
 Louis WalshParty Guest | Party Guest |
 Kevin WhatelyDI Robert Lewis | DI Robert Lewis |