When a celebrated TV show host returns to his hometown in the South, his family is there to remind him that going home is no vacation!
| Actor | Role |
|---|---|
 Martin LawrenceRoscoe Jenkins | Roscoe Jenkins |
 James Earl JonesPapa Jenkins | Papa Jenkins |
 Margaret AveryMamma Jenkins | Mamma Jenkins |
 Joy BryantBianca Kittles | Bianca Kittles |
 Cedric the EntertainerClyde Stubb | Clyde Stubb |
 Nicole Ari ParkerLucinda Allen | Lucinda Allen |
 Michael Clarke DuncanSheriff Otis Jenkins | Sheriff Otis Jenkins |
 Mike EppsReggie | Reggie |
 Mo'NiqueBetty | Betty |
 Damani RobertsJamaal Jenkins | Jamaal Jenkins |
 Brooke LyonsAmy | Amy |
 Louis C.K.Marty | Marty |
 Liz MikelRuthie | Ruthie |
 Carol SuttonMs. Pearl | Ms. Pearl |
 Deetta WestMs. Addy | Ms. Addy |
| BBrandin JenkinsJunior | Junior |
 Erin CummingsSally | Sally |