Dr. Abraham Van Helsing is granted immortality by the Catholic Church until he can hunt down the last vampire prince.
| Actor | Role |
|---|---|
 Rhett GilesDr. Abraham Van Helsing | Dr. Abraham Van Helsing |
 Paul LoganDracula | Dracula |
 Andreas BeckettSebastien | Sebastien |
 Denise BoutteArianna | Arianna |
 Brent FalcoEmily | Emily |
| AAlix HenningYvonne | Yvonne |
 Jared CohnRoman | Roman |
| JJames AshbyDominic | Dominic |
| DDrew BerencNorris | Norris |
| TTrina RobinsonElena | Elena |
| CClaudia Katz MinnickLeona | Leona |
| NNadra MacuishPaula | Paula |
| EEd FlanaganYavanivitch | Yavanivitch |
 Matt DallasTodd | Todd |
| SShannon KempDetective Donn Franco | Detective Donn Franco |
| LLawrence SaraWilson | Wilson |
| UUlf BjorlinWalsh | Walsh |
| RRenée Danielle De PonteDiana | Diana |
 Edward DeRuiterJake | Jake |
| AAnthony TurkFather Cefalu | Father Cefalu |
 Amanda WardNatalia | Natalia |
| LLisa ClarkEssence | Essence |
| AAnne MetcalfeToothy Vampire | Toothy Vampire |