Buckskin Hamilton guides a wagon train across the wasteland, caring well for the pioneers he escorts, but hoping to solve the murder of his brother by one of the travellers.
| Actor | Role |
|---|---|
 William S. HartBuckskin Hamilton | Buckskin Hamilton |
 Jane NovakJane Washburn | Jane Washburn |
 Robert McKimDonald Washburn | Donald Washburn |
 Lloyd BaconGuy Merton | Guy Merton |
 Leo PiersonBilly Hamilton | Billy Hamilton |
 Bert SprotteBrick Muldoon | Brick Muldoon |
 Charles ArlingThe Captain | The Captain |