The queen of soul, Aretha Franklin, and four of the biggest female hitmakers in contemporary pop, Mariah Carey, Celine Dion, Gloria Estefan, and Shania Twain, join forces for this once-in-a-lifetime concert event where they sing their hits and team up for a variety of ensemble performances. The night also includes an appearance by legendary songwriter Carole King.
| Actor | Role |
|---|---|
 Aretha FranklinSelf - Performer | Self - Performer |
 Mariah CareySelf - Performer | Self - Performer |
 Carole KingSelf - Performer | Self - Performer |
 Céline DionSelf - Performer | Self - Performer |
 Gloria EstefanSelf - Performer | Self - Performer |
 Shania TwainSelf - Performer | Self - Performer |
 Jennifer AnistonSelf - Host | Self - Host |
 Joan OsborneSelf - Host | Self - Host |
 Patricia ArquetteSelf - Host | Self - Host |
 Teri HatcherSelf - Host | Self - Host |
 Sarah McLachlanSelf - Host | Self - Host |
 Sarah Jessica ParkerSelf - Host | Self - Host |
 Susan SarandonSelf - Host | Self - Host |