Starting with a cruel joke – a couple of callow men make a bet that one of them can seduce the woman sharing their train compartment – the film charts the relationship that develops between a small-town girl in the big city, and the brother of the man who has heartlessly seduced and abandoned her.
| Actor | Role |
|---|---|
 Irene DunneNancy Andrews | Nancy Andrews |
 Robert MontgomeryTommy Duncan | Tommy Duncan |
 Preston FosterSteve Duncan | Steve Duncan |
 Eugene PalletteElmer | Elmer |
 Esther DaleAunt Mathilda | Aunt Mathilda |
 Walter CatlettBilly Ross | Billy Ross |
 Samuel S. HindsUncle | Uncle |
 Dick ForanFrank | Frank |
 June ClydeClarisse | Clarisse |
 Richard DaviesRichard | Richard |
 Kathryn AdamsKaty | Katy |
 Phyllis BarrySheila | Sheila |
 Mary GordonMiss Brady | Miss Brady |
 Paul FixReporter | Reporter |
 Chester CluteMr. Beck | Mr. Beck |
 Fortunio BonanovaImpresario | Impresario |
 Hugh BeaumontHugh the Bridegroom | Hugh the Bridegroom |