Uncle Tom and Eliza's child are sold to Haley, a slave dealer. When Eliza learns that her son is to be taken from her, she steals the boy and runs away.
| Actor | Role |
|---|---|
 Henry HallamUncle Tom | Uncle Tom |
 Anna Q. NilssonEliza - a Runaway Slave | Eliza - a Runaway Slave |
 Hal ClementsSimon Legree | Simon Legree |
 Miriam CooperTopsy - Aunt Ophelia's Slave | Topsy - Aunt Ophelia's Slave |
 Guy CoombsGeorge Harris | George Harris |
 Helen LindrothMrs. Shelby | Mrs. Shelby |
 James VincentSt. Clair | St. Clair |
| MMary SwigertAunt Ophelia | Aunt Ophelia |
 Doris HollisterLittle Eva | Little Eva |
 George Hollister Jr.Baby Harris | Baby Harris |
| JJames B. RossHaley | Haley |
| RR. BignoldShelby | Shelby |
 Kenean BuelLawyer Marks | Lawyer Marks |