UFC 279: Diaz vs. Ferguson was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on September 10, 2022, at the T-Mobile Arena in Paradise, Nevada, part of the Las Vegas Metropolitan Area, United States. A welterweight bout between Khamzat Chimaev and former lightweight title challenger (also The Ultimate Fighter 5 lightweight winner) Nate Diaz was originally expected to headline the event. However at the weigh-ins, Chimaev weighed in at 178.5 pounds, 7.5 pounds over the welterweight non-title limit and the bout was cancelled. As a result, the organization opted to shuffle a trio of fights: a new main event featuring Diaz against former interim UFC Lightweight Champion (also The Ultimate Fighter: Team Lesnar vs. Team dos Santos welterweight winner) Tony Ferguson, who was originally scheduled to face Li Jingliang in a welterweight bout, was then set.
| Actor | Role |
|---|---|
 Nate DiazSelf | Self |
 Tony FergusonSelf | Self |
 Khamzat ChimaevSelf | Self |
 Kevin HollandSelf | Self |
 Daniel RodriguezSelf | Self |
 Li JingliangSelf | Self |
 Irene AldanaSelf | Self |
 Macy ChiassonSelf | Self |
 Johnny WalkerSelf | Self |
 Ion CuțelabaSelf | Self |
 Julian ErosaSelf | Self |
 Hakeem DawoduSelf | Self |
 Jailton AlmeidaSelf | Self |
 Anton TurkaljSelf | Self |
 Denis TiuliulinSelf | Self |
 Jamie PickettSelf | Self |
 Chris BarnettSelf | Self |
 Jake CollierSelf | Self |
 Norma Dumont VianaSelf | Self |
 Danyelle WolfSelf | Self |
 Heili AlatengSelf | Self |
 Chad AnheligerSelf | Self |
 Elise ReedSelf | Self |
 Melissa MartinezSelf | Self |
 Yohan LainesseSelf | Self |
 Darian WeeksSelf | Self |