In order to escape from the mob, an African-American man must disguise himself as a white man.
| Actor | Role |
|---|---|
 Lenny HenryMiles Pope | Miles Pope |
 Frank LangellaLeland Carver | Leland Carver |
 Anne-Marie JohnsonKristi | Kristi |
 James Earl JonesJames Earl Jones | James Earl Jones |
 Peggy LiptonRita | Rita |
 Melvin Van PeeblesTaxi Driver | Taxi Driver |
 J.T. WalshHouston | Houston |
 Andreas KatsulasAnthony | Anthony |
 Charles LaneDuane | Duane |
 Bill RaymondGrunfeld | Grunfeld |
 Ruth BrownMartha | Martha |
 Michael Jai WhiteAlley Guy #1 | Alley Guy #1 |
 Hazelle GoodmanMiles' Neighbor #1 | Miles' Neighbor #1 |
 R. Lee ErmeyHouston’s Boss | Houston’s Boss |
 Michael McKeanHarvey Cooper | Harvey Cooper |
 Judson ScottIago | Iago |
 Laura SchaeferStewardess | Stewardess |
 Lynne GriffinEmilia | Emilia |
 Austin PendletonDirector of Othello | Director of Othello |
 Christopher CollinsFrank LaMotta | Frank LaMotta |
| FFantasia OwensRuth | Ruth |
 Joe BellanJanitor | Janitor |
 Richard GanoungRoderigo | Roderigo |
 Shane DixonFBI Agent on Catwalk | FBI Agent on Catwalk |
| IIlona WilsonLola | Lola |
 Mik ScribaPolice Sergeant | Police Sergeant |
 Michael BaskinAirplane Husband | Airplane Husband |
 Tracy Brooks SwopeAirplane Wife | Airplane Wife |