Tweety Bird is being taken by his mistress, Granny, on a trip across a prairie in a horse-drawn wagon when they are attacked by a tribe of Indian cats, all of whom are Sylvester or Sylvester variants.
| Actor | Role |
|---|---|
 Mel BlancSylvester / Tweety / Cat Chief (voice) | Sylvester / Tweety / Cat Chief (voice) |
 Bea BenaderetGranny (voice) | Granny (voice) |