The popular cartoon cat and mouse are thrown into a feature film. The story has the twosome trying to help an orphan girl who is being berated and exploited by a greedy guardian.
| Actor | Role |
|---|---|
 Richard KindTom (voice) | Tom (voice) |
 Dana HillJerry (voice) | Jerry (voice) |
 Anndi McAfeeRobyn (voice) | Robyn (voice) |
 Tony JayLickboot (voice) | Lickboot (voice) |
 Rip TaylorCaptain Kiddie (voice) | Captain Kiddie (voice) |
 Henry GibsonApplecheek (voice) | Applecheek (voice) |
 Michael BellFerdinand / Straycatcher #1 (voice) | Ferdinand / Straycatcher #1 (voice) |
 Ed GilbertPuggsy / Daddy Starling (voice) | Puggsy / Daddy Starling (voice) |
 David L. LanderFrankie Da Flea (voice) | Frankie Da Flea (voice) |
 Howard MorrisSquawk (voice) | Squawk (voice) |
 Sydney LassickStraycatcher #2 (voice) | Straycatcher #2 (voice) |
| RRaymond McLeodAlleycat / Bulldog (voice) | Alleycat / Bulldog (voice) |
| MMitchel D. MooreAlleycat (voice) | Alleycat (voice) |
| SScott WojahnAlleycat (voice) | Alleycat (voice) |
 Tino InsanaPatrolman (voice) | Patrolman (voice) |
| DDon MessickDroopy (voice) | Droopy (voice) |
 B.J. WardWoman (voice) | Woman (voice) |
 Greg BursonMoving Man (voice) | Moving Man (voice) |
 Charlotte RaeAunt Figg (voice) | Aunt Figg (voice) |