After being evicted from their old house by Tom's owner for causing major damage, cat and mouse Tom and Jerry enter a race entitled the "Fabulous Super Race" to win a mansion.
| Actor | Role |
|---|---|
 Charlie AdlerGrammy (voice) | Grammy (voice) |
 Jeff BennettSteed (voice) | Steed (voice) |
 John DiMaggioJ.W. / Spike (voice) | J.W. / Spike (voice) |
 Jess HarnellBuzz Blister / Film Director (voice) | Buzz Blister / Film Director (voice) |
 Tom KennyGorthan / Whale (voice) | Gorthan / Whale (voice) |
 Bill KoppTom / Frank (voice) | Tom / Frank (voice) |
 Tress MacNeilleSoccer Mom / Lady / Tour Girl (voice) | Soccer Mom / Lady / Tour Girl (voice) |
 Rob PaulsenIrving / Dave (voice) | Irving / Dave (voice) |
 Billy WestBiff Buzzard / President of Hollywood / Squirty (voice) | Biff Buzzard / President of Hollywood / Squirty (voice) |
 J. Grant AlbrechtClown-O / Security Guard (voice) | Clown-O / Security Guard (voice) |
| TThom PintoComputer / Guard (voice) | Computer / Guard (voice) |
 Neil RossDr. Professor / Director (voice) | Dr. Professor / Director (voice) |
| RRenna NightingaleLauren | Lauren |