Tokimeki Memorial brings together the twelve young girls from Kirameki High School, but revolves around the main girl, Fujisaki Shiori. The story starts at the beginning of the third school year, which is the last year before the main character can choose a girl and date her at the graduation.
| Actor | Role |
|---|---|
 Mami KingetsuShiori Fujisaki (voice) | Shiori Fujisaki (voice) |
| SSachiko SugawaraSaki Nijino (voice) | Saki Nijino (voice) |
 Sakura TangeMinori Akiho (voice) | Minori Akiho (voice) |
| AAkiko Sekine(voice) | (voice) |
| MMasayo Kawaguchi(voice) | (voice) |
| MMikiko Kurihara(voice) | (voice) |
 Shiho Kikuchi(voice) | (voice) |
| AAyako Kurosaki(voice) | (voice) |
| AAyako Sasaki(voice) | (voice) |
| KKurin Yoshiki(voice) | (voice) |
 Masaaki Tsukada(voice) | (voice) |
| MMiki Ono(voice) | (voice) |
| NNarumi Tsunoda(voice) | (voice) |
 Nobuo Tobita(voice) | (voice) |
 Rei Igarashi(voice) | (voice) |
 Ryoka Yuzuki(voice) | (voice) |
 Tomoko Naka(voice) | (voice) |
| TToshio Kawai(voice) | (voice) |
| YYoko Teppozuka(voice) | (voice) |
 Yuji Ueda(voice) | (voice) |