 Charlie AdlerBuster Bunny / Usher (voice) | Buster Bunny / Usher (voice) |
 Tress MacNeilleBabs Bunny / Big Boo / Babs' Mother / Emily Duff / Roseanne Barr / Barbara Walters / Arsenio Hall / Additional Voices (voice) | Babs Bunny / Big Boo / Babs' Mother / Emily Duff / Roseanne Barr / Barbara Walters / Arsenio Hall / Additional Voices (voice) |
 Joe AlaskeyPlucky Duck / Tupelo Toad / Johnny Carson / Ed McMahon / Elmer Fudd / Additional Voices (voice) | Plucky Duck / Tupelo Toad / Johnny Carson / Ed McMahon / Elmer Fudd / Additional Voices (voice) |
 Don MessickHamton J. Pig / Radio Announcer (voice) | Hamton J. Pig / Radio Announcer (voice) |
 Jonathan WintersWade Pig / Superman (voice) | Wade Pig / Superman (voice) |
 Edie McClurgWinnie Pig (voice) | Winnie Pig (voice) |
 Frank WelkerUncle Stinky Pig / Byron Basset / Furrball / Little Beeper / Gogo Dodo / Vinnie / Mac Duff / Additional Voices (voice) | Uncle Stinky Pig / Byron Basset / Furrball / Little Beeper / Gogo Dodo / Vinnie / Mac Duff / Additional Voices (voice) |
 Cree SummerElmyra Duff / Mary Melody / Oprah Winfrey (voice) | Elmyra Duff / Mary Melody / Oprah Winfrey (voice) |
 Sorrell BookeBig Daddy Boo (voice) | Big Daddy Boo (voice) |
 Rob PaulsenFowlmouth / Johnny Pew / Banjo the Woodpile Possum / Mr. Hitcher / Manager / Additional Voices (voice) | Fowlmouth / Johnny Pew / Banjo the Woodpile Possum / Mr. Hitcher / Manager / Additional Voices (voice) |
 Maurice LaMarcheDizzy Devil / David Letterman / Horatio / Theatre Voice (voice) | Dizzy Devil / David Letterman / Horatio / Theatre Voice (voice) |
 Gail MatthiusShirley the Loon / Sissy Boo (voice) | Shirley the Loon / Sissy Boo (voice) |
 Kath SoucieFifi La Fume / Little Boo / Little Sneezer / Bimbette Skunk (voice) (as Kath Souci) | Fifi La Fume / Little Boo / Little Sneezer / Bimbette Skunk (voice) (as Kath Souci) |
 Candi MiloSweetie Pie (voice) | Sweetie Pie (voice) |
 Paul JulianRoad Runner (archive sound) (uncredited) | Road Runner (archive sound) (uncredited) |
