All the couples are back for a wedding in Las Vegas, but plans for a romantic weekend go awry when their various misadventures get them into some compromising situations that threaten to derail the big event.
| Actor | Role |
|---|---|
 Adam BrodyIsaac | Isaac |
 Michael EalyDominic | Dominic |
 Jerry FerraraJeremy Kern | Jeremy Kern |
 Meagan GoodMya | Mya |
 Regina HallCandace Hall | Candace Hall |
 Kevin HartCedric Ward | Cedric Ward |
 Dennis HaysbertUncle Eddie | Uncle Eddie |
 Taraji P. HensonLauren Harris | Lauren Harris |
 Terrence JMichael Hanover | Michael Hanover |
 Jenifer LewisLoretta | Loretta |
 Romany MalcoZeke Freeman | Zeke Freeman |
 Wendi McLendon-CoveyTish | Tish |
 Gary OwenBennett | Bennett |
 Gabrielle UnionKristen | Kristen |
 David WaltonTerrell | Terrell |
 La La AnthonySonia | Sonia |
 Jim PiddockDeclan | Declan |
 Wendy WilliamsGail | Gail |
 Caleel HarrisDuke | Duke |
 Angela Elayne GibbsAdele | Adele |
 LuenellAunt Winnie | Aunt Winnie |
| CChelsea DawnGirl in Pool | Girl in Pool |
| FFonzworth BentleyJackson | Jackson |
 Ernestine JohnsonPool Waitress | Pool Waitress |
 George WallaceRandy the Dealer | Randy the Dealer |
 Ray ProsciaMarcel Haffer | Marcel Haffer |
 Will PackerJP The Driver | JP The Driver |
 Janina GavankarVanessa Martinez | Vanessa Martinez |
 Malea RoseEileen | Eileen |
 Nicholas GuilakChef Cotillard | Chef Cotillard |