A young cavalry doctor treats very sick Indians against orders, whom are forced to stay on unhealthy land, which could lead to a war.
| Actor | Role |
|---|---|
 Robert FrancisDr. Allen Seward | Dr. Allen Seward |
 Donna ReedLaurie MacKaye | Laurie MacKaye |
 May WynnManyi-ten | Manyi-ten |
 Philip CareyCapt. Peter Blake (as Phil Carey) | Capt. Peter Blake (as Phil Carey) |
 Onslow StevensCol. Ethan Waters | Col. Ethan Waters |
 Peggy ConverseMrs. Martha Walters | Mrs. Martha Walters |
 Roy RobertsSgt. Creever | Sgt. Creever |
 Jack KellyLt. Raymond | Lt. Raymond |
 Stuart RandallChief Satanta | Chief Satanta |
 Eugene IglesiasRed Leaf | Red Leaf |
 Frank De KovaIsatai | Isatai |
 John War EagleChief Quanah | Chief Quanah |
 Ralph DumkeDr. Gibson | Dr. Gibson |
 James BestLt. Finlay (uncredited) | Lt. Finlay (uncredited) |