 Whoopi GoldbergKatie Coltrane | Katie Coltrane |
 Armin Mueller-StahlElizar Kane | Elizar Kane |
 Juliet LandauDr. Veronica Shade | Dr. Veronica Shade |
 Bud CortSpinner | Spinner |
 Stephen McHattieEdge | Edge |
 George NewbernTheodore Rex (voice) | Theodore Rex (voice) |
 Carol KaneMolly Rex (voice) | Molly Rex (voice) |
 Richard RoundtreeCommissioner Lynch | Commissioner Lynch |
 Jack RileyAlaric | Alaric |
 Peter MacKenzieAlex Summers | Alex Summers |
 Joe DallesandroRogan | Rogan |
 Tony T. JohnsonSebastian | Sebastian |
| SSusie CoelhoDr. Armitraj | Dr. Armitraj |
 Peter KwongToymaker | Toymaker |
 Edith DiazElla | Ella |
| RRobert Martin RobinsonKnife | Knife |
 Dee BooherMeanest Woman Truck Driver | Meanest Woman Truck Driver |
 William BoyettDesk Sergeant | Desk Sergeant |
| MMarius MazmanianButler | Butler |
 Noon OrsattiAdam | Adam |
 Hilary ShepardSarah Jiminez | Sarah Jiminez |
| LLisa PapatzimasNew Eden Secretary | New Eden Secretary |
 Michael SharrettNew Eden Volunteer | New Eden Volunteer |
 Jan RabsonTina Rex / Voice Performer (voice) | Tina Rex / Voice Performer (voice) |
| CCharles ChiodoGuy in the Bag (voice) | Guy in the Bag (voice) |
 Patricia HealyReporter #2 | Reporter #2 |
 James MurrayTina the Waitress (puppeteer) | Tina the Waitress (puppeteer) |
 Stephen ChiodoGuy in the Bag (puppeteer) | Guy in the Bag (puppeteer) |
| EEdward ChiodoCaterpillar (puppeteer) | Caterpillar (puppeteer) |
| PPons MaarTheodore Rex (performer) | Theodore Rex (performer) |
