Three strangers embark on a life-changing journey on a fateful bus ride. As the road presents challenges, each character faces his or her own shortcomings, not knowing where life will lead next.
| Actor | Role |
|---|---|
 Joan CollinsAlice Chicoy | Alice Chicoy |
 Jayne MansfieldCamille Oakes | Camille Oakes |
 Dan DaileyErnest Horton | Ernest Horton |
 Rick JasonJohnny Chicoy | Johnny Chicoy |
 Betty Lou KeimNorma | Norma |
 Dolores MichaelsMildred Pritchard | Mildred Pritchard |
 Larry KeatingElliott Pritchard | Elliott Pritchard |
 Robert BrayMorse | Morse |
 Kathryn GivneyBernice Pritchard | Bernice Pritchard |
 Dee PollockEd "Pimples" Carson | Ed "Pimples" Carson |
 Will WrightVan Brunt | Van Brunt |
 Milton FromeStanton | Stanton |
 Joe DevlinMike | Mike |
| RRoy BourgeoisNot listed | Not listed |
 Mary CarrollNot listed | Not listed |
 Harry CarterNot listed | Not listed |
| TTom GreenwayNot listed | Not listed |