 Charles BronsonJoe Valachi | Joe Valachi |
 Lino VenturaVito Genovese | Vito Genovese |
 Jill IrelandMaria Reina Valachi | Maria Reina Valachi |
 Walter ChiariDominick Petrilli, aka "Gap" | Dominick Petrilli, aka "Gap" |
 Joseph WisemanSalvatore Maranzano | Salvatore Maranzano |
 Gerald S. O'LoughlinRyan, federal agent | Ryan, federal agent |
 Amedeo NazzariGaetano Reina | Gaetano Reina |
 Fausto TozziAlbert Anastasia | Albert Anastasia |
 Pupella MaggioLetizia Reina | Letizia Reina |
 Angelo InfantiLucky Luciano | Lucky Luciano |
 Guido LeontiniTony Bender | Tony Bender |
 María BaxaDonna Petrillo | Donna Petrillo |
 Mario PilarSalierno | Salierno |
 Franco BorelliBuster | Buster |
 Alessandro SperliGiuseppe 'Joe the Boss' Masseria | Giuseppe 'Joe the Boss' Masseria |
| NNatasha ChevelevJane | Jane |
 Anthony DawsonFederal Investigator | Federal Investigator |
 Fred VallecaBuck | Buck |
 John AlarimoSteven Ferrigno (uncredited) | Steven Ferrigno (uncredited) |
 Calogero AzzarettoMan of the clan (uncredited) | Man of the clan (uncredited) |
 Joe Don BakerIrish member of Valachi gang (uncredited) | Irish member of Valachi gang (uncredited) |
| SSteve BelloiseWinnie (uncredited) | Winnie (uncredited) |
 Angelo BoscariolGangster (uncredited) | Gangster (uncredited) |
 Nestore CavaricciPrisoner with Valachi (uncredited) | Prisoner with Valachi (uncredited) |
| GGiacomo De MichelisAugie (uncredited) | Augie (uncredited) |
 Bruno Di LuiaLuciano's Henchman (uncredited) | Luciano's Henchman (uncredited) |
 Arny FreemanWarden (uncredited) | Warden (uncredited) |
 Alfonso GigantiWedding party guest (uncredited) | Wedding party guest (uncredited) |
 Ron GilbertPrison Guard (uncredited) | Prison Guard (uncredited) |
 Frank GioFrank (uncredited) | Frank (uncredited) |
