When her doctor recommends that a widow pursue her unfulfilled life ambitions, he doesn't realize that she has always wanted to be a spy. Sending a letter to her congressman gets her an interview with the CIA and accidentally gets her an assignment to Morocco for a supposed easy task of picking up an encrypted code book. When the agency realizes their mistake, they send a super-agent to watch over her. Both are taken prisoner and the real agent is injured, leaving Mrs. Pollifax to use her considerable wits to help them escape and to save the day.
| Actor | Role |
|---|---|
 Angela LansburyEmily Pollifax | Emily Pollifax |
 Thomas Ian GriffithJack Farrell | Jack Farrell |
 Ed BishopCarstairs | Carstairs |
 Paul BirchardBishop | Bishop |
| MMichelle ReadAlice | Alice |
| TTommy O'NeillFranz | Franz |
| PPaul KennedyHans | Hans |
 Joseph LongAleksei Yagoda | Aleksei Yagoda |
 Gerry O'BrienHaggarty | Haggarty |
 John LightRobin Hughes-Wright | Robin Hughes-Wright |
 Todd BoyceMason | Mason |
| PPatricia MartinLady Palisibury | Lady Palisibury |
 Daisy DonovanAlexandra | Alexandra |
| RRobert BoydBaron Von Roelen | Baron Von Roelen |
 Jacqueline PearceNot listed | Not listed |