Told in Documentary form, the film depicts a group of five British film critics and politicians who venture off into the West Virginian wilderness in search of the "Tony Blair Witch" which may or may not be related to British Prime Minister Tony Blair.
| Actor | Role |
|---|---|
 Tim JahnAlexander Walker | Alexander Walker |
 Michael A. MartinezTony Blair | Tony Blair |
| DDominic FantazziNigel | Nigel |
| CC. Alan PloegsmaCalan Fairbrain | Calan Fairbrain |
| GGreg S. CampbellGregory Wallin | Gregory Wallin |
| DDavid M. WoodChief Redneck | Chief Redneck |
| GGeorge N. ThompsonRedneck | Redneck |
 Brian KlapsteinRedneck | Redneck |
| JJoshua ThompsonYoung Hick | Young Hick |
| CChip BrookesSilly American | Silly American |
| RRaymond L. MartinezRedneck Attacker | Redneck Attacker |
 Wayne HorineNobody | Nobody |
| SShannon R. Anderson IIIMurchison, Surley Video Store Clerk | Murchison, Surley Video Store Clerk |
| CChristy SandbergGNC Store Clerk | GNC Store Clerk |
| AAnthony ForkClueless Interviewee | Clueless Interviewee |
| SShawn FrancheckSmarmy Interviewee | Smarmy Interviewee |