Escaping death, a Hebrew infant is raised in a royal household to become a prince. Upon discovery of his true heritage, Moses embarks on a personal quest to reclaim his destiny as the leader and liberator of the Hebrew people.
| Actor | Role |
|---|---|
 Charlton HestonMoses | Moses |
 Yul BrynnerRameses | Rameses |
 Anne BaxterNefretiri | Nefretiri |
 Edward G. RobinsonDathan | Dathan |
 Yvonne De CarloSephora | Sephora |
 Debra PagetLilia | Lilia |
 John DerekJoshua | Joshua |
 Cedric HardwickeSethi | Sethi |
 Nina FochBithiah | Bithiah |
 Martha ScottYochabel | Yochabel |
 Judith AndersonMemnet | Memnet |
 Vincent PriceBaka | Baka |
 John CarradineAaron | Aaron |
 Olive DeeringMiriam | Miriam |
 Douglass DumbrilleJannes | Jannes |
 Frank De KovaAbiram | Abiram |
 Henry WilcoxonPentaur | Pentaur |
 Eduard FranzJethro | Jethro |
 Donald CurtisMered | Mered |
 Lawrence DobkinHur Ben Caleb | Hur Ben Caleb |
 H.B. WarnerAmminadab | Amminadab |
 Julia FayeElisheba | Elisheba |
| LLisa MitchellJethro's Daughter | Jethro's Daughter |
| NNoelle WilliamsJethro's Daughter | Jethro's Daughter |
 Joanna MerlinJethro's Daughter | Jethro's Daughter |
| PPat RichardJethro's Daughter | Jethro's Daughter |
| JJoyce van der VeenJethro's Daughter | Jethro's Daughter |
| DDiane HallJethro's Daughter | Jethro's Daughter |
| AAbbas El BoughdadlyRameses' Charioteer | Rameses' Charioteer |
 Fraser Clarke HestonThe Infant Moses | The Infant Moses |