Rookie cop Denny Colt returns from the beyond as The Spirit, a hero whose mission is to fight against the bad forces from the shadows of Central City. The Octopus, who kills anyone unfortunate enough to see his face, has other plans:g to wipe out the entire city.
| Actor | Role |
|---|---|
 Gabriel MachtThe Spirit / Denny Colt | The Spirit / Denny Colt |
 Eva MendesSand Saref | Sand Saref |
 Samuel L. JacksonOctopus | Octopus |
 Scarlett JohanssonSilken Floss | Silken Floss |
 Sarah PaulsonEllen Dolan | Ellen Dolan |
 Dan LauriaDolan | Dolan |
 Paz VegaPlaster of Paris | Plaster of Paris |
 Eric BalfourMahmoud | Mahmoud |
 Jaime KingLorelei Rox | Lorelei Rox |
 Stana KaticMorgenstern | Morgenstern |
 Frank MillerLiebowitz | Liebowitz |
 Johnny SimmonsYoung Spirit | Young Spirit |
 Seychelle GabrielYoung Sand | Young Sand |
 Dan GerrityDetective Sussman | Detective Sussman |
| KKimberly CoxDamsel in Distress | Damsel in Distress |
 Richard PortnowDonenfeld | Donenfeld |
 Louis LombardiPathos, etc. | Pathos, etc. |
| EEmily CheungOnlooker #4 | Onlooker #4 |
 Brian Neal LuceroThug 1 | Thug 1 |
 Bill PopeOnlooker #2 | Onlooker #2 |