The Simpsons: America's First Family is a 50 minute program which features the production of The Simpsons, celebrating the 10th anniversary of the series.
| Actor | Role |
|---|---|
 Matt GroeningSelf | Self |
 Hank AzariaSelf | Self |
 James L. BrooksSelf | Self |
 Nancy CartwrightSelf | Self |
 Dan CastellanetaSelf | Self |
 Alf ClausenSelf | Self |
 Mel GibsonSelf | Self |
 Al JeanSelf | Self |
 Tom JonesSelf | Self |
 Julie KavnerSelf | Self |
| SSteven Dean MooreSelf | Self |
 Mike ScullySelf | Self |
 Yeardley SmithSelf | Self |
| DDan SniersonSelf | Self |
| CCharles SolomonSelf | Self |
| JJoe WackSelf | Self |
| LLance WilderSelf | Self |
 Zoë BallSelf | Self |