Concerned about his friend's cocaine use, Dr. Watson tricks Sherlock Holmes into travelling to Vienna, where Holmes enters the care of Sigmund Freud. Freud attempts to solve the mysteries of Holmes' subconscious, while Holmes devotes himself to solving a mystery involving the kidnapping of Lola Deveraux.
| Actor | Role |
|---|---|
 Alan ArkinDr. Sigmund Freud | Dr. Sigmund Freud |
 Vanessa RedgraveLola Deveraux | Lola Deveraux |
 Robert DuvallDr. John H. Watson | Dr. John H. Watson |
 Nicol WilliamsonSherlock Holmes | Sherlock Holmes |
 Laurence OlivierProfessor James Moriarty | Professor James Moriarty |
 Joel GreyLowenstein | Lowenstein |
 Samantha EggarMary Morstan Watson | Mary Morstan Watson |
 Jeremy KempBaron Karl von Leinsdorf | Baron Karl von Leinsdorf |
 Charles GrayMycroft Holmes | Mycroft Holmes |
 RégineMadame | Madame |
 Anna QuayleFreda | Freda |
 Georgia BrownMrs. Freud | Mrs. Freud |
 Jill TownsendMrs. Holmes | Mrs. Holmes |
 John BirdBerger | Berger |
 Alison LeggattMrs. Hudson | Mrs. Hudson |
 Frederick JaegerMarker | Marker |
 Erik ChittyThe Butler | The Butler |
 Jack MayDr. Schultz | Dr. Schultz |
 Gertan KlauberThe Pasha | The Pasha |
 Leon GreeneSquire Holmes | Squire Holmes |
| SSheila Shand GibbsNun | Nun |
 Erich PadalewskiStation Master | Station Master |