After the events of Despicable Me 3, we follow Kyle and his secret life when Gru and his family are gone.
| Actor | Role |
|---|---|
 Miranda CosgroveMargo (voice) | Margo (voice) |
 Dana Gaier EllisEdith (voice) | Edith (voice) |
 Nhev ScharrelAgnes (voice) | Agnes (voice) |
 Pierre CoffinMinions (voice) | Minions (voice) |
 Brian T. DelaneyMailman (voice) | Mailman (voice) |
 Tara StrongShop Owner / Bella's Owner (voice) | Shop Owner / Bella's Owner (voice) |