 Sidney TolerCharlie Chan | Charlie Chan |
 Benson FongTommy Chan | Tommy Chan |
 Mantan MorelandBirmingham Brown, Chauffeur | Birmingham Brown, Chauffeur |
 Robert HomansCapt. Flynn | Capt. Flynn |
 I. Stanford JolleyRolf Brot, alias Ralph Brett | Rolf Brot, alias Ralph Brett |
 Virginia BrissacMrs. Marsh | Mrs. Marsh |
 Jack NortonWillie Rand | Willie Rand |
 Janet ShawGloria Bayne | Gloria Bayne |
 Ben CarterBen Carter | Ben Carter |
 Victoria FaustHulda Swenson / Janet Carter | Hulda Swenson / Janet Carter |
| HHelen DeverellDiane Hall | Diane Hall |
 Leonard MudieHorace Karloss | Horace Karloss |
 Reid KilpatrickMr. Chester, program announcer | Mr. Chester, program announcer |
 Emmett VoganMr. Hamilton | Mr. Hamilton |
 Crane WhitleyHenchman Cooper | Henchman Cooper |
 Kernan CrippsDetective (uncredited) | Detective (uncredited) |
 Charles JordanNelson (uncredited) | Nelson (uncredited) |
 Kenner G. KempPolice Radio Expert (uncredited) | Police Radio Expert (uncredited) |
 Milton KibbeeHerbert Sinclair (uncredited) | Herbert Sinclair (uncredited) |
 Frank MayoDet. Hodge (uncredited) | Det. Hodge (uncredited) |
| Leonard MudieHorace Karlos (uncredited) | Horace Karlos (uncredited) |
| TTom QuinnChemist (uncredited) | Chemist (uncredited) |
 Charles SherlockSgt. McGraw (uncredited) | Sgt. McGraw (uncredited) |
 Charles WagenheimRausch (uncredited) | Rausch (uncredited) |
