After being released from prison, a man known as The Rambler stumbles upon a strange mystery as he attempts a dangerous journey through treacherous back roads and small towns en route to reconnecting with his long lost brother.
| Actor | Role |
|---|---|
 Dermot MulroneyThe Rambler | The Rambler |
 Lindsay PulsipherThe Girl | The Girl |
 Natasha LyonneCheryl | Cheryl |
 Carrie LazarSusan | Susan |
 James CadyThe Scientist | The Scientist |
| SScott SharotThe Driver | The Driver |
| PPaul BlottDale | Dale |
 Robyn ReedeRoberta / Pawn Shop Owner | Roberta / Pawn Shop Owner |
 Christopher DempseyBob | Bob |
| FFran MartoneShirley | Shirley |
| SSherril JohnsonScientist's Daughter / Bar Girl | Scientist's Daughter / Bar Girl |
| MMatt OlsenDaryl | Daryl |
| JJed MaheuKenny | Kenny |
 Christo DimassisKevin | Kevin |
| RRagini BhaumikHussy | Hussy |
| JJohn HardmanIvar | Ivar |
| NNestor BirnerBill | Bill |
| RRoger M. MayerFat Man | Fat Man |
 Chris RanneyClerk | Clerk |
 Elana KrauszFamily Woman | Family Woman |
 Stephen EilandHook Fighter | Hook Fighter |
 Vincent E. McDanielBoxer | Boxer |
| MMichael BuccioniGerald | Gerald |
 Johnnie HectorTracy | Tracy |
| JJon Kristian MooreLouis at Poker Table | Louis at Poker Table |
| HHugh ElliotJim in Prison | Jim in Prison |
 Steven Michael QuezadaGuard #1 | Guard #1 |
| CClay WalkerGuard #2 | Guard #2 |
 Jerry G. AngeloScum Bag #1 | Scum Bag #1 |
| AAnthony ParkerScum Bag #2 | Scum Bag #2 |