 Sandra BullockMargaret Tate | Margaret Tate |
 Ryan ReynoldsAndrew Paxton | Andrew Paxton |
 Malin AkermanGertrude | Gertrude |
 Craig T. NelsonJoe Paxton | Joe Paxton |
 Mary SteenburgenGrace Paxton | Grace Paxton |
 Betty WhiteGrandma Annie | Grandma Annie |
 Denis O'HareMr. Gilbertson | Mr. Gilbertson |
 Oscar NuñezRamone | Ramone |
 Aasif MandviBob Spaulding | Bob Spaulding |
 Michael NouriChairman Bergen | Chairman Bergen |
 Gregg EdelmanLead Counsel Malloy | Lead Counsel Malloy |
 Michael MosleyChuck | Chuck |
 Dale PlaceJim McKittrick | Jim McKittrick |
 Alicia HuntCoffee Barista | Coffee Barista |
 Alexis GarciaImmigration Clerk | Immigration Clerk |
| KKortney AdamsColden Books Receptionist | Colden Books Receptionist |
| CChris WhitneyMedivac Pilot | Medivac Pilot |
| JJerrell Lee WesleyJordan | Jordan |
 Phyllis KayMrs. McKittrick | Mrs. McKittrick |
 Kate LaceyParty Guest | Party Guest |
| GGene FlemingStore Owner | Store Owner |
 Mary Linda RapelyeExecutive Secretary | Executive Secretary |
 Anne FletcherJill | Jill |
| BB. JohnsonGuy in Office | Guy in Office |
 John FranchiTaxicab Driver (uncredited) | Taxicab Driver (uncredited) |
| DDan GriffinBusinessman / Pedestrian on Sidewalk (uncredited) | Businessman / Pedestrian on Sidewalk (uncredited) |
 London HallWedding and Reception Guest (uncredited) | Wedding and Reception Guest (uncredited) |
 Dan MarshallLawyer at Publishing Company (uncredited) | Lawyer at Publishing Company (uncredited) |
 Ron MurphyWedding Guest (uncredited) | Wedding Guest (uncredited) |
 Niecy NashStewardess (uncredited) | Stewardess (uncredited) |
